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Dr. Shanfeng Wang

Associate Professor 

Ph.D., Akron: Biomaterials and Tissue Engineering, Polymer Chemistry, Physics, and Rheology.

Brief Bio

Born in 1977, Dr. Wang earned his B.S. in Polymer Science and Engineering with a second major in Applied Mathematics from East China University of Science and Technology (ECUST, Shanghai) in 1997. Continuing at ECUST, he completed his M.S. in Polymer Science and Engineering in 2000, where he studied synthesis and photophysical properties of novel conjugated polymers. Dr. Wang received his Ph.D. in Polymer Science from the University of Akron, Ohio in December 2003. His doctoral studies focused on chain dynamics of binary polymer blends using rheological and pulsed gradient NMR methods. In 2004, Dr. Wang joined Mayo Clinic (Rochester, Minnesota) as a Research Fellow where he developed a series of novel crosslinkable and degradable polymeric systems for bone and nerve regeneration, and investigated the interactions between cells/tissues and polymer substrates/scaffolds. In 2007 Dr. Wang joined the Department of Materials Science and Engineering at the University of Tennessee as a tenure-track assistant professor. Dr. Wang was promoted to associate professor with tenure in 2013. His research interests include biomaterials and tissue engineering, polymer chemistry, physics and rheology. Dr. Wang held a joint faculty appointment with the Biosciences Division at Oak Ridge National Laboratory in 2010-2013 and he is a core faculty member in the Institute of Biomedical Engineering at the University of Tennessee. Dr. Wang has more than 60 research papers, including 4 invited book chapters and 3 review articles. He has also contributed to over 120 research presentations at conferences.

Research Areas

  • Rational design, synthesis, physical properties, and processing of polymeric biomaterials for various tissue engineering applications
  • Smart biomaterials such as shape memory polymers, biomimetic or bionic polymer/nanocomposite systems for medical applications
  • Fabrication of biodegradable scaffolds and microfluidics, and effects of material properties and scaffold features on in vitro cell responses and in vivo tissue growth
  • Cancer therapy and gene therapy based on polymeric nanoparticle carriers

Selected Awards and Honors

2008 Guest Professorship, East China University of Science and Technology (ECUST), Shanghai, China
2006 Gordon Research Conference Travel Award, New London, CT
2002 Outstanding Thesis Award, ECUST, Shanghai, China
2000 Dow Fellowship Sponsored by Dow Chemical Co., ECUST, Shanghai, China

Professional Activities

  • Society of Rheology (SoR), Member since 2001
  • American Physical Society (APS), Member since 2002
  • American Chemical Society (ACS), Member since 2003
  • Materials Research Society (MRS), Member since 2006
  • American Institute of Chemical Engineers (AIChE), Member since 2006, Senior member since 2008
  • Guest Editor of the special issue of “Formation and Photoluminescence of Fluorescent Polymers” and Lead Guest Editor for the annual special issue of “Polymeric Biomaterials for Tissue Engineering Applications”, International Journal of Polymer Science, 2009-2011
  • Member of Editorial Board for Journal of Biotechnology & Biomaterials, 2010-present
  • Guest Editor for the Special Issue of “Advanced Nanohybrid Materials: Surface Modification and Applications,” Journal of Nanomaterials, 2011
  • Guest Editor for the Special Issue of “”Polymer Nanocomposite Processing, Characterization, and Applications,” ”Journal of Nanomaterials, 2013.

Selected Publications

Wu, X.; Wang, S.* “Biomimetic Calcium Carbonate Concentric Microgrooves with Tunable Width for Promoting MC3T3-E1 Cell Functions” Advanced Healthcare Materials 2013, 2(2), 326-33.

Wu, X.; Wang, S.* “Regulating MC3T3-E1 Cells on Poly(ε-caprolactone) Honeycomb Films Prepared Using a Surfactant-free Breath Figure Method in a Water-miscible Solvent” ACS Applied Materials & Interfaces 2012, 4(9), 4966-75. (Cover Story)

Cai, L.; Zhang, L.; Dong, J.; Wang, S.* “Photo-cured Biodegradable Polymeric Substrates of Varying Stiffness and Microgroove Dimensions for Promoting Nerve Cell Guidance and Differentiation” Langmuir 2012, 28(34), 12557-68.

Cai, L.; Chen, J.; Rondinone, A.; Wang, S.* “Injectable and Biodegradable Nanohybrid Polymers with Simultaneously Enhanced Stiffness and Toughness for Bone Repair” Advanced Functional Materials 2012, 22(15), 3181-90.

Cai, L.; Lu, J.; Sheen, V.; Wang, S.* “Optimal Poly(L-lysine) Grafting Density in Hydrogels for Promoting Nerve Progenitor Cell Functions” Biomacromolecules 2012, 12(5), 1663-74.

Wang, K.; Cai, L.; Zhang, L.; Dong, J.; Wang, S.* “Biodegradable Polymer Substrates with Concentric Microgrooves for Regulating MC3T3 Cell Behavior” Advanced Healthcare Materials 2012, 1(3), 292-301.

Wang, K.; Cai, L.; Jesse, S.; Wang, S.* “Poly(ε-caprolactone) Banded Spherulites and Interaction with MC3T3-E1 Cells” Langmuir 2012, 28(9), 4382-95.

Cai, L.; Lu, J.; Sheen, V.; Wang, S.* “Promoting Nerve Cell Functions on Hydrogels Grafted with Poly(L-lysine)” Biomacromolecules 2012, 12(2), 342-9.

Cai, L.; Lu, J.; Sheen, V.; Wang, S.* “Lubricated Biodegradable Elastomers for Regulating Nerve Cell Behavior and Fabricating Nerve Conduits with a Compositional Gradient” Biomacromolecules 2012, 12(2), 358-68. (Featured in Global Medical Discovery)

Cai, L.; Wang, S.* “Parabolic Dependence of Material Properties and Cell Behavior on the Composition of Polymer Networks via Simultaneously Controlling Crosslinking Density and Crystallinity” Biomaterials 2010, 31(29), 7423-34.


Selected Patents

Wang, S.; Yaszemski, M. J.; Lu, L.; Currier, B. L. “Block Copolymer of Polycaprolactone and Poly(propylene fumarate)” International Publication Number: WO/2006/055940, International Application Number: PCT/US2005/042240.

Wang, S.; Lu, L.; Yaszemski, M. J. “Photocrosslinkable Poly(e-caprolactone fumarate)” International Publication Number: WO/2006/053031, International Application Number: PCT/US2005/40571.

Wang, S.; Lu, L.; Yaszemski, M. J. “Hydrophilic/hydrophobic Hybrid Polymer Networks Based on Poly(caprolactone fumarate) (PCLF), Poly(ethylene glycol fumarate) (PEGF), and PEGF-co-PCLF” International Publication Number: WO/2006/118987, International Application Number: PCT/US2006/016156.

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